Reduction-Triggered Breakable Micelles of Amphiphilic Polyamide Amine-g-Polyethylene Glycol for Methotrexate Delivery

Reduction-triggered breakable polymeric micelles incorporated with MTX were prepared using amphiphilic PAA-g-PEG copolymers having S–S bonds in the backbone. The micelles were spherical with diameters less than 70 nm. The micelles could encapsulate the hydrophobic MTX in the hydrophobic core. The dr...

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Detalles Bibliográficos
Autores principales: Huang, Yihang, Liu, Jun, Cui, Yani, Li, Huanan, Sun, Yong, Fan, Yujiang, Zhang, Xingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005151/
https://www.ncbi.nlm.nih.gov/pubmed/24895626
http://dx.doi.org/10.1155/2014/904634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005151/
https://www.ncbi.nlm.nih.gov/pubmed/24895626
http://dx.doi.org/10.1155/2014/904634

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