Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases

PURPOSE: To analyze the complications and their managements in Descemet's stripping endothelial keratoplasty (DSEK) in consecutive 430 cases by single surgeon in a tertiary eye hospital. MATERIALS AND METHODS: 430 eyes of 366 patients with endothelial dysfunctions scheduled for DSEK, were analy...

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Autores principales: Basak, Samar K, Basak, Soham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005239/
https://www.ncbi.nlm.nih.gov/pubmed/24008797
http://dx.doi.org/10.4103/0301-4738.116484
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author Basak, Samar K
Basak, Soham
author_facet Basak, Samar K
Basak, Soham
author_sort Basak, Samar K
collection PubMed
description PURPOSE: To analyze the complications and their managements in Descemet's stripping endothelial keratoplasty (DSEK) in consecutive 430 cases by single surgeon in a tertiary eye hospital. MATERIALS AND METHODS: 430 eyes of 366 patients with endothelial dysfunctions scheduled for DSEK, were analyzed retrospectively. In all cases donor dissection was performed manually, and ‘Taco’ insertion and unfolding technique was used. Intra-operative and postoperative complications with their managements and outcomes were reviewed retrospectively. Periodic endothelial cell density was analyzed for each patient till the last visit. Follow-up period was between 3 to 60 months (mean 18.7 months). RESULTS: 13 (3.0%) eyes had operative complications during donor dissection and 16 (3.7%) had during recipient procedure. In 7 (1.6%) eyes, donor lenticule was replaced with a new one during the surgery. In early postoperative period, 21 (4.9%) eyes had donor dislocation and 12 (2.8%) eyes had air-induced pupillary block; and they were managed immediately. 2 cases had primary graft failure and in 1 case had postoperative bacterial endophthalmitis requiring evisceration. In late postoperative period, 48 (11.3%) eyes had secondary glaucoma and 14 (3.3%) eyes had late secondary graft failure. Endothelial rejection occurred in 5 (1.2%) cases. Mean endothelial cell loss was 19.7% after 3 months and 54.2% after 5 years. Total graft failure in this series was 31 (7.2%) and in 17 cases re-DSEK was performed successfully. CONCLUSIONS: Both operative and postoperative complications do occur in DSEK. Most of these complications can be managed by medical or appropriate surgical means. Some of the complications can be avoided and reduced with experience.
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spelling pubmed-40052392014-05-01 Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases Basak, Samar K Basak, Soham Indian J Ophthalmol Original Article PURPOSE: To analyze the complications and their managements in Descemet's stripping endothelial keratoplasty (DSEK) in consecutive 430 cases by single surgeon in a tertiary eye hospital. MATERIALS AND METHODS: 430 eyes of 366 patients with endothelial dysfunctions scheduled for DSEK, were analyzed retrospectively. In all cases donor dissection was performed manually, and ‘Taco’ insertion and unfolding technique was used. Intra-operative and postoperative complications with their managements and outcomes were reviewed retrospectively. Periodic endothelial cell density was analyzed for each patient till the last visit. Follow-up period was between 3 to 60 months (mean 18.7 months). RESULTS: 13 (3.0%) eyes had operative complications during donor dissection and 16 (3.7%) had during recipient procedure. In 7 (1.6%) eyes, donor lenticule was replaced with a new one during the surgery. In early postoperative period, 21 (4.9%) eyes had donor dislocation and 12 (2.8%) eyes had air-induced pupillary block; and they were managed immediately. 2 cases had primary graft failure and in 1 case had postoperative bacterial endophthalmitis requiring evisceration. In late postoperative period, 48 (11.3%) eyes had secondary glaucoma and 14 (3.3%) eyes had late secondary graft failure. Endothelial rejection occurred in 5 (1.2%) cases. Mean endothelial cell loss was 19.7% after 3 months and 54.2% after 5 years. Total graft failure in this series was 31 (7.2%) and in 17 cases re-DSEK was performed successfully. CONCLUSIONS: Both operative and postoperative complications do occur in DSEK. Most of these complications can be managed by medical or appropriate surgical means. Some of the complications can be avoided and reduced with experience. Medknow Publications & Media Pvt Ltd 2014-02 /pmc/articles/PMC4005239/ /pubmed/24008797 http://dx.doi.org/10.4103/0301-4738.116484 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Basak, Samar K
Basak, Soham
Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases
title Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases
title_full Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases
title_fullStr Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases
title_full_unstemmed Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases
title_short Complications and management in Descemet's stripping endothelial keratoplasty: Analysis of consecutive 430 cases
title_sort complications and management in descemet's stripping endothelial keratoplasty: analysis of consecutive 430 cases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005239/
https://www.ncbi.nlm.nih.gov/pubmed/24008797
http://dx.doi.org/10.4103/0301-4738.116484
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