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Epidermal growth factor induces platelet-activating factor production through receptors transactivation and cytosolic phospholipase A(2) in ovarian cancer cells
BACKGROUND: Among the pro-inflammatory lipid mediators, platelet-activating factor (PAF) is a major primary and secondary messenger that binds to the PAF-receptor (PAFR). Epidermal growth factor (EGF) is a polypeptide growth factor that binds to the EGF-receptor (EGFR). Evidence suggests that both P...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005630/ https://www.ncbi.nlm.nih.gov/pubmed/24721622 http://dx.doi.org/10.1186/1757-2215-7-39 |