Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells

Small interfering RNA (siRNA)-based RNA interference (RNAi) is widely used for target gene silencing in various organisms. We previously showed that 8-nt-long 5′ proximal nucleotides, which include seed sequence (positions 2–8 from the 5′ end of guide strand), and the complementary sequence of the p...

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Detalles Bibliográficos
Autores principales: Takahashi, Tomoko, Zenno, Shuhei, Ishibashi, Osamu, Takizawa, Toshihiro, Saigo, Kaoru, Ui-Tei, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005638/
https://www.ncbi.nlm.nih.gov/pubmed/24561616
http://dx.doi.org/10.1093/nar/gku153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005638/
https://www.ncbi.nlm.nih.gov/pubmed/24561616
http://dx.doi.org/10.1093/nar/gku153

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