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A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data

DNA methylation is an important epigenetic modification that has essential roles in cellular processes including gene regulation, development and disease and is widely dysregulated in most types of cancer. Recent advances in sequencing technology have enabled the measurement of DNA methylation at si...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Conneely, Karen N., Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005660/
https://www.ncbi.nlm.nih.gov/pubmed/24561809
http://dx.doi.org/10.1093/nar/gku154