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A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data
DNA methylation is an important epigenetic modification that has essential roles in cellular processes including gene regulation, development and disease and is widely dysregulated in most types of cancer. Recent advances in sequencing technology have enabled the measurement of DNA methylation at si...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005660/ https://www.ncbi.nlm.nih.gov/pubmed/24561809 http://dx.doi.org/10.1093/nar/gku154 |