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Deciphering the rules by which dynamics of mRNA secondary structure affect translation efficiency in Saccharomyces cerevisiae

Messenger RNA (mRNA) secondary structure decreases the elongation rate, as ribosomes must unwind every structure they encounter during translation. Therefore, the strength of mRNA secondary structure is assumed to be reduced in highly translated mRNAs. However, previous studies in vitro reported a p...

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Detalles Bibliográficos
Autores principales: Mao, Yuanhui, Liu, HuiLing, Liu, Yanlin, Tao, Shiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005662/
https://www.ncbi.nlm.nih.gov/pubmed/24561808
http://dx.doi.org/10.1093/nar/gku159