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Isoform-level gene signature improves prognostic stratification and accurately classifies glioblastoma subtypes

Molecular stratification of tumors is essential for developing personalized therapies. Although patient stratification strategies have been successful; computational methods to accurately translate the gene-signature from high-throughput platform to a clinically adaptable low-dimensional platform ar...

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Detalles Bibliográficos
Autores principales: Pal, Sharmistha, Bi, Yingtao, Macyszyn, Luke, Showe, Louise C., O'Rourke, Donald M., Davuluri, Ramana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005667/
https://www.ncbi.nlm.nih.gov/pubmed/24503249
http://dx.doi.org/10.1093/nar/gku121