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Sumoylation of the THO complex regulates the biogenesis of a subset of mRNPs

Assembly of messenger ribonucleoparticles (mRNPs) is a pivotal step in gene expression, but only a few molecular mechanisms contributing to its regulation have been described. Here, through a comprehensive proteomic survey of mRNP assembly, we demonstrate that the SUMO pathway specifically controls...

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Detalles Bibliográficos
Autores principales: Bretes, Hugo, Rouviere, Jérôme O., Leger, Thibaut, Oeffinger, Marlene, Devaux, Frédéric, Doye, Valérie, Palancade, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005672/
https://www.ncbi.nlm.nih.gov/pubmed/24500206
http://dx.doi.org/10.1093/nar/gku124