Ribonuclease L and metal-ion–independent endoribonuclease cleavage sites in host and viral RNAs

Ribonuclease L (RNase L) is a metal-ion–independent endoribonuclease associated with antiviral and antibacterial defense, cancer and lifespan. Despite the biological significance of RNase L, the RNAs cleaved by this enzyme are poorly defined. In this study, we used deep sequencing methods to reveal...

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Detalles Bibliográficos
Autores principales: Cooper, Daphne A., Jha, Babal K., Silverman, Robert H., Hesselberth, Jay R., Barton, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005677/
https://www.ncbi.nlm.nih.gov/pubmed/24500209
http://dx.doi.org/10.1093/nar/gku118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005677/
https://www.ncbi.nlm.nih.gov/pubmed/24500209
http://dx.doi.org/10.1093/nar/gku118

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