Cargando…

MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17∼92 microRNA cluster

While functional mature microRNAs (miRNAs) are small ∼22 base oligonucleotides that target specific mRNAs, miRNAs are initially expressed as long transcripts (pri-miRNAs) that undergo sequential processing to yield the mature miRNAs. We have previously reported that the pri-miR-17∼92 cluster adopts...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaulk, Steven G., Xu, Zhizhong, Glover, Mark J. N., Fahlman, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005684/
https://www.ncbi.nlm.nih.gov/pubmed/24520115
http://dx.doi.org/10.1093/nar/gku133