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Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility
Hydroxyl Radical Footprinting (HRF) is a tried-and-tested method for analysis of the tertiary structure of RNA and for identification of protein footprints on RNA. The hydroxyl radical reaction breaks accessible parts of the RNA backbone, thereby allowing ribose accessibility to be determined by det...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005689/ https://www.ncbi.nlm.nih.gov/pubmed/24569351 http://dx.doi.org/10.1093/nar/gku167 |