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Type III restriction endonucleases are heterotrimeric: comprising one helicase–nuclease subunit and a dimeric methyltransferase that binds only one specific DNA

Fundamental aspects of the biochemistry of Type III restriction endonucleases remain unresolved despite being characterized by numerous research groups in the past decades. One such feature is the subunit stoichiometry of these hetero-oligomeric enzyme complexes, which has important implications for...

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Detalles Bibliográficos
Autores principales: Butterer, Annika, Pernstich, Christian, Smith, Rachel M., Sobott, Frank, Szczelkun, Mark D., Tóth, Júlia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005696/
https://www.ncbi.nlm.nih.gov/pubmed/24510100
http://dx.doi.org/10.1093/nar/gku122