Influence of hydrophobic and electrostatic residues on SARS-coronavirus S2 protein stability: Insights into mechanisms of general viral fusion and inhibitor design

Severe acute respiratory syndrome (SARS) is an acute respiratory disease caused by the SARS-coronavirus (SARS-CoV). SARS-CoV entry is facilitated by the spike protein (S), which consists of an N-terminal domain (S1) responsible for cellular attachment and a C-terminal domain (S2) that mediates viral...

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Detalles Bibliográficos
Autores principales: Aydin, Halil, Al-Khooly, Dina, Lee, Jeffrey E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Blackwell 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005712/
https://www.ncbi.nlm.nih.gov/pubmed/24519901
http://dx.doi.org/10.1002/pro.2442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005712/
https://www.ncbi.nlm.nih.gov/pubmed/24519901
http://dx.doi.org/10.1002/pro.2442

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