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Metformin Inhibits the IL-6-Induced Epithelial-Mesenchymal Transition and Lung Adenocarcinoma Growth and Metastasis

OBJECTIVE: Epithelial-mesenchymal transition (EMT) plays an important role in cancer tumorigenesis. However, the underlying mechanisms of EMT in lung adenocarcinoma, and how this process might be inhibited, remain to be explored. This study investigated the role of IL-6 in lung adenocarcinoma cell E...

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Detalles Bibliográficos
Autores principales: Zhao, Zhongquan, Cheng, Xiaoming, Wang, Yubo, Han, Rui, Li, Li, Xiang, Tong, He, Luhang, Long, Haixia, Zhu, Bo, He, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005743/
https://www.ncbi.nlm.nih.gov/pubmed/24789104
http://dx.doi.org/10.1371/journal.pone.0095884