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HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA

Upon muscle injury the high mobility group box 1 (HMGB1) protein is up-regulated and secreted to initiate reparative responses. Here we show that HMGB1 controls myogenesis both in vitro and in vivo, during development and after adult muscle injury. HMGB1 expression in muscle cells is regulated at th...

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Detalles Bibliográficos
Autores principales: Dormoy-Raclet, Virginie, Cammas, Anne, Celona, Barbara, Lian, Xian Jin, van der Giessen, Kate, Zivojnovic, Marija, Brunelli, Silvia, Riuzzi, Francesca, Sorci, Guglielmo, Wilhelm, Brian T., Di Marco, Sergio, Donato, Rosario, Bianchi, Marco E., Gallouzi, Imed-Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005793/
https://www.ncbi.nlm.nih.gov/pubmed/24005720
http://dx.doi.org/10.1038/ncomms3388