The role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECs

The cyclic AMP sensor, EPAC1, activates AP1-mediated transcription in HUVECs. Correspondingly, induction of the SOCS3 minimal promoter by EPAC1 requires a single AP1 site that constitutively binds phosphorylated (Ser63) c-Jun in DNA-pull-down assays. c-Jun (Ser63) becomes further phosphorylated foll...

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Detalles Bibliográficos
Autores principales: Wiejak, Jolanta, Dunlop, Julia, Yarwood, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005914/
https://www.ncbi.nlm.nih.gov/pubmed/24631457
http://dx.doi.org/10.1016/j.febslet.2014.02.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005914/
https://www.ncbi.nlm.nih.gov/pubmed/24631457
http://dx.doi.org/10.1016/j.febslet.2014.02.038

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