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Cellular accumulation of Cys326-OGG1 protein complexes under conditions of oxidative stress

The common Ser326Cys polymorphism in the base excision repair protein 8-oxoguanine glycosylase 1 is associated with a reduced capacity to repair oxidative DNA damage particularly under conditions of intracellular oxidative stress and there is evidence that Cys326-OGG1 homozygous individuals have inc...

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Detalles Bibliográficos
Autores principales: Kaur, M.P., Guggenheim, E.J., Pulisciano, C., Akbar, S., Kershaw, R.M., Hodges, N.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005915/
https://www.ncbi.nlm.nih.gov/pubmed/24680828
http://dx.doi.org/10.1016/j.bbrc.2014.03.044