Cargando…

The role of extracellular Tau in the spreading of neurofibrillary pathology

The microtubule-associated protein (MAP) tau plays a critical role in the pathogenesis of Alzheimer’s disease (AD) and several related disorders collectively known as tauopathies. Development of tau pathology is associated with progressive neuronal loss and cognitive decline. In the brains of AD pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Medina, Miguel, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005959/
https://www.ncbi.nlm.nih.gov/pubmed/24795568
http://dx.doi.org/10.3389/fncel.2014.00113