Cargando…
The role of extracellular Tau in the spreading of neurofibrillary pathology
The microtubule-associated protein (MAP) tau plays a critical role in the pathogenesis of Alzheimer’s disease (AD) and several related disorders collectively known as tauopathies. Development of tau pathology is associated with progressive neuronal loss and cognitive decline. In the brains of AD pat...
Autores principales: | Medina, Miguel, Avila, Jesús |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005959/ https://www.ncbi.nlm.nih.gov/pubmed/24795568 http://dx.doi.org/10.3389/fncel.2014.00113 |
Ejemplares similares
-
Editorial: Untangling the Role of Tau in Physiology and Pathology
por: Medina, Miguel, et al.
Publicado: (2020) -
The Involvement of Cholinergic Neurons in the Spreading of Tau Pathology
por: Simón, Diana, et al.
Publicado: (2013) -
The Role of Microglia in the Spread of Tau: Relevance for Tauopathies
por: Perea, Juan R., et al.
Publicado: (2018) -
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer’s disease
por: Zhang, Zhentao, et al.
Publicado: (2014) -
Intracellular and Extracellular Tau
por: Avila, Jesús
Publicado: (2010)