Cargando…

mTOR signaling and its roles in normal and abnormal brain development

Target of rapamycin (TOR) was first identified in yeast as a target molecule of rapamycin, an anti-fugal and immunosuppressant macrolide compound. In mammals, its orthologue is called mammalian TOR (mTOR). mTOR is a serine/threonine kinase that converges different extracellular stimuli, such as nutr...

Descripción completa

Detalles Bibliográficos
Autores principales: Takei, Nobuyuki, Nawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005960/
https://www.ncbi.nlm.nih.gov/pubmed/24795562
http://dx.doi.org/10.3389/fnmol.2014.00028