Fatty acids increase neuronal hypertrophy of Pten knockdown neurons

Phosphatase and tensin homolog (Pten) catalyzes the reverse reaction of PI3K by dephosphorylating PIP3 to PIP2. This negatively regulates downstream Akt/mTOR/S6 signaling resulting in decreased cellular growth and proliferation. Co-injection of a lentivirus knocking Pten down with a control lentivir...

Descripción completa

Detalles Bibliográficos
Autores principales: Fricano, Catherine J., DeSpenza, Tyrone, Frazel, Paul W., Li, Meijie, O'Malley, A. James, Westbrook, Gary L., Luikart, Bryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006057/
https://www.ncbi.nlm.nih.gov/pubmed/24795563
http://dx.doi.org/10.3389/fnmol.2014.00030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006057/
https://www.ncbi.nlm.nih.gov/pubmed/24795563
http://dx.doi.org/10.3389/fnmol.2014.00030

Ejemplares similares