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Loss of the TNFα function inhibits Wnt/β-catenin signaling, exacerbates obesity development in adolescent spontaneous obese mice

Tumor necrosis factor alpha (TNFα) is an adipokine involved in the regulation of cell differentiation and lipid metabolism, but its specific role has not been clearly understood. We validated a hypothesis that loss of TNFα function would inhibit Wnt/β-catenin signaling and accelerate adipogenesis in...

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Detalles Bibliográficos
Autores principales: Gong, Maolei, Liu, Chuanguo, Zhang, Liang, Zhang, Hongbin, Pan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006126/
https://www.ncbi.nlm.nih.gov/pubmed/24522555
http://dx.doi.org/10.1007/s11010-014-1987-5