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Smad3 Signaling Activates Bone Marrow-Derived Fibroblasts in Renal Fibrosis

Recent studies have demonstrated that bone marrow-derived fibroblasts contribute significantly to the pathogenesis of renal fibrosis. However, the signaling mechanisms underlying the activation of bone marrow-derived fibroblasts in the kidney are incompletely understood. Since TGF-β1/Smad3 signaling...

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Detalles Bibliográficos
Autores principales: Chen, Jiyuan, Xia, Yunfeng, Lin, Xia, Feng, Xin-Hua, Wang, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006302/
https://www.ncbi.nlm.nih.gov/pubmed/24614197
http://dx.doi.org/10.1038/labinvest.2014.43