Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry

In vivo beta-2 microglobulin (β(2)m) forms amyloid fibrils that are associated with the disease dialysis-related amyloidosis. Here, electrospray ionisation-ion mobility spectrometry-mass spectrometry has been used to compare the oligomers formed from wild-type β(2)m with those formed from a variant...

Descripción completa

Detalles Bibliográficos
Autores principales: Leney, Aneika C., Pashley, Clare L., Scarff, Charlotte A., Radford, Sheena E., Ashcroft, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006425/
https://www.ncbi.nlm.nih.gov/pubmed/24336936
http://dx.doi.org/10.1039/c3mb70420c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006425/
https://www.ncbi.nlm.nih.gov/pubmed/24336936
http://dx.doi.org/10.1039/c3mb70420c

Ejemplares similares