Determining Effects of Non-synonymous SNPs on Protein-Protein Interactions using Supervised and Semi-supervised Learning

Single nucleotide polymorphisms (SNPs) are among the most common types of genetic variation in complex genetic disorders. A growing number of studies link the functional role of SNPs with the networks and pathways mediated by the disease-associated genes. For example, many non-synonymous missense SN...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Han, Jing Ginger, Shyu, Chi-Ren, Korkin, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006705/
https://www.ncbi.nlm.nih.gov/pubmed/24784581
http://dx.doi.org/10.1371/journal.pcbi.1003592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006705/
https://www.ncbi.nlm.nih.gov/pubmed/24784581
http://dx.doi.org/10.1371/journal.pcbi.1003592

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