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Discovery and Confirmation of Ligand Binding Specificities of the Schistosoma japonicum Polarity Protein Scribble

BACKGROUND: Schistosomiasis is a chronic debilitating parasitic disease that afflicts more than 200 million individuals worldwide. Long-term administration of chemotherapy with the single available drug, praziquantel, has led to growing concerns about drug resistance. The PSD-95/Dlg/ZO-1 (PDZ) domai...

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Detalles Bibliográficos
Autores principales: Cai, Pengfei, Mu, Yi, Piao, Xianyu, Hou, Nan, Liu, Shuai, Gao, Youhe, Wang, Heng, Chen, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006718/
https://www.ncbi.nlm.nih.gov/pubmed/24784152
http://dx.doi.org/10.1371/journal.pntd.0002837