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Mutations in Four Glycosyl Hydrolases Reveal a Highly Coordinated Pathway for Rhodopsin Biosynthesis and N-Glycan Trimming in Drosophila melanogaster

As newly synthesized glycoproteins move through the secretory pathway, the asparagine-linked glycan (N-glycan) undergoes extensive modifications involving the sequential removal and addition of sugar residues. These modifications are critical for the proper assembly, quality control and transport of...

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Detalles Bibliográficos
Autores principales: Rosenbaum, Erica E., Vasiljevic, Eva, Brehm, Kimberley S., Colley, Nansi Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006722/
https://www.ncbi.nlm.nih.gov/pubmed/24785692
http://dx.doi.org/10.1371/journal.pgen.1004349