Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon

The ribonuclease III enzyme Drosha has a central role in the biogenesis of microRNA (miRNA) by binding and cleaving hairpin structures in primary RNA transcripts into precursor miRNAs (pre-miRNAs). Many miRNA genes are located within protein-coding host genes and cleaved by Drosha in a manner that i...

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Detalles Bibliográficos
Autores principales: Havens, Mallory A., Reich, Ashley A., Hastings, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006729/
https://www.ncbi.nlm.nih.gov/pubmed/24786770
http://dx.doi.org/10.1371/journal.pgen.1004312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006729/
https://www.ncbi.nlm.nih.gov/pubmed/24786770
http://dx.doi.org/10.1371/journal.pgen.1004312

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