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Trans-spliced Heat Shock Protein 90 Modulates Encystation in Giardia lamblia

BACKGROUND: Hsp90 from Giardia lamblia is expressed by splicing of two independently transcribed RNA molecules, coded by genes named HspN and HspC located 777 kb apart. The reasons underlying such unique trans-splicing based generation of GlHsp90 remain unclear. PRINCIPLE FINDING: In this study usin...

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Detalles Bibliográficos
Autores principales: Nageshan, Rishi Kumar, Roy, Nainita, Ranade, Shatakshi, Tatu, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006730/
https://www.ncbi.nlm.nih.gov/pubmed/24786776
http://dx.doi.org/10.1371/journal.pntd.0002829