Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction

Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and mortality and, whilst smoking remains the single most important risk factor, COPD risk is heritable. Of 26 independent genomic regions showing association with lung function in genome-wide association studies, el...

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Detalles Bibliográficos
Autores principales: Wain, Louise V., Sayers, Ian, Soler Artigas, María, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma'en, Sin, Don D., Bossé, Yohan, Nickle, David, Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelinsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia, Shrine, Nick R. G., Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P., Tobin, Martin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006731/
https://www.ncbi.nlm.nih.gov/pubmed/24786987
http://dx.doi.org/10.1371/journal.pgen.1004314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006731/
https://www.ncbi.nlm.nih.gov/pubmed/24786987
http://dx.doi.org/10.1371/journal.pgen.1004314

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