An In Vivo EGF Receptor Localization Screen in C. elegans Identifies the Ezrin Homolog ERM-1 as a Temporal Regulator of Signaling

The subcellular localization of the epidermal growth factor receptor (EGFR) in polarized epithelial cells profoundly affects the activity of the intracellular signaling pathways activated after EGF ligand binding. Therefore, changes in EGFR localization and signaling are implicated in various human...

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Detalles Bibliográficos
Autores principales: Haag, Andrea, Gutierrez, Peter, Bühler, Alessandra, Walser, Michael, Yang, Qiutan, Langouët, Maeva, Kradolfer, David, Fröhli, Erika, Herrmann, Christina J., Hajnal, Alex, Escobar-Restrepo, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006739/
https://www.ncbi.nlm.nih.gov/pubmed/24785082
http://dx.doi.org/10.1371/journal.pgen.1004341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006739/
https://www.ncbi.nlm.nih.gov/pubmed/24785082
http://dx.doi.org/10.1371/journal.pgen.1004341

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