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Dicer Regulates Differentiation and Viability during Mouse Pancreatic Cancer Initiation

miRNA levels are altered in pancreatic ductal adenocarcinoma (PDA), the most common and lethal pancreatic malignancy, and intact miRNA processing is essential for lineage specification during pancreatic development. However, the role of miRNA processing in PDA has not been explored. Here we study th...

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Detalles Bibliográficos
Autores principales: Morris, John P., Greer, Renee, Russ, Holger A., von Figura, Guido, Kim, Grace E., Busch, Anke, Lee, Jonghyeob, Hertel, Klemens J., Kim, Seung, Mcmanus, Michael, Hebrok, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006805/
https://www.ncbi.nlm.nih.gov/pubmed/24788257
http://dx.doi.org/10.1371/journal.pone.0095486