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Transcriptome Profiling of Human Ulcerative Colitis Mucosa Reveals Altered Expression of Pathways Enriched in Genetic Susceptibility Loci

Human colonic mucosa altered by inflammation due to ulcerative colitis (UC) displays a drastically altered pattern of gene expression compared with healthy tissue. We aimed to understand the underlying molecular pathways influencing these differences by analyzing three publically-available, independ...

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Detalles Bibliográficos
Autores principales: Cardinale, Christopher J., Wei, Zhi, Li, Jin, Zhu, Junfei, Gu, Mengnan, Baldassano, Robert N., Grant, Struan F. A., Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006814/
https://www.ncbi.nlm.nih.gov/pubmed/24788701
http://dx.doi.org/10.1371/journal.pone.0096153