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Searching for Genomic Region of High-Fat Diet-Induced Type 2 Diabetes in Mouse Chromosome 2 by Analysis of Congenic Strains

SMXA-5 mice are a high-fat diet-induced type 2 diabetes animal model established from non-diabetic SM/J and A/J mice. By using F2 intercross mice between SMXA-5 and SM/J mice under feeding with a high-fat diet, we previously mapped a major diabetogenic QTL (T2dm2sa) on chromosome 2. We then produced...

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Detalles Bibliográficos
Autores principales: Kobayashi, Misato, Ohno, Tamio, Ihara, Kunio, Murai, Atsushi, Kumazawa, Mayumi, Hoshino, Hiromi, Iwanaga, Koichiro, Iwai, Hiroshi, Hamana, Yoshiki, Ito, Mikako, Ohno, Kinji, Horio, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006839/
https://www.ncbi.nlm.nih.gov/pubmed/24789282
http://dx.doi.org/10.1371/journal.pone.0096271