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Immunosurveillance of senescent cancer cells by natural killer cells

We recently dissected how senescent tumors can trigger complementing signaling pathways that mobilize natural killer (NK) cells to eliminate malignant cells. In addition to cell-intrinsic effects on proliferation, senescence induces the production of chemokine (C-C motif) ligand 2 (CCL2), which recr...

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Detalles Bibliográficos
Autores principales: Iannello, Alexandre, Raulet, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006855/
https://www.ncbi.nlm.nih.gov/pubmed/24800169
http://dx.doi.org/10.4161/onci.27616