The Position of DNA Cleavage by TALENs and Cell Synchronization Influences the Frequency of Gene Editing Directed by Single-Stranded Oligonucleotides

With recent technological advances that enable DNA cleavage at specific sites in the human genome, it may now be possible to reverse inborn errors, thereby correcting a mutation, at levels that could have an impact in a clinical setting. We have been developing gene editing, using single-stranded DN...

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Detalles Bibliográficos
Autores principales: Rivera-Torres, Natalia, Strouse, Bryan, Bialk, Pawel, Niamat, Rohina A., Kmiec, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006861/
https://www.ncbi.nlm.nih.gov/pubmed/24788536
http://dx.doi.org/10.1371/journal.pone.0096483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006861/
https://www.ncbi.nlm.nih.gov/pubmed/24788536
http://dx.doi.org/10.1371/journal.pone.0096483

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