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Sparstolonin B, a Novel Plant Derived Compound, Arrests Cell Cycle and Induces Apoptosis in N-Myc Amplified and N-Myc Nonamplified Neuroblastoma Cells

Neuroblastoma is one of the most common solid tumors and accounts for ∼15% of all the cancer related deaths in the children. Despite the standard therapy for advanced disease including chemotherapy, surgery, and radiation, the mortality rate remains high for these patients. Hence, novel therapeutic...

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Detalles Bibliográficos
Autores principales: Kumar, Ambrish, Fan, Daping, DiPette, Donald J., Singh, Ugra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006872/
https://www.ncbi.nlm.nih.gov/pubmed/24788776
http://dx.doi.org/10.1371/journal.pone.0096343