Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation

NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MIC) A andB, and UL16-binding proteins (ULBP)1–6) induce...

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Detalles Bibliográficos
Autores principales: Fielding, Ceri A., Aicheler, Rebecca, Stanton, Richard J., Wang, Eddie C. Y., Han, Song, Seirafian, Sepehr, Davies, James, McSharry, Brian P., Weekes, Michael P., Antrobus, P. Robin, Prod'homme, Virginie, Blanchet, Fabien P., Sugrue, Daniel, Cuff, Simone, Roberts, Dawn, Davison, Andrew J., Lehner, Paul J., Wilkinson, Gavin W. G., Tomasec, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006889/
https://www.ncbi.nlm.nih.gov/pubmed/24787765
http://dx.doi.org/10.1371/journal.ppat.1004058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006889/
https://www.ncbi.nlm.nih.gov/pubmed/24787765
http://dx.doi.org/10.1371/journal.ppat.1004058

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