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Novel Natural Mutations in the Hepatitis B Virus Reverse Transcriptase Domain Associated with Hepatocellular Carcinoma

BACKGROUND/AIM: Hepatitis B Virus (HBV) mutations play a role in the development of hepatocellular carcinoma (HCC). However, the association between HBV polymerase gene mutations and HCC has not been reported. In this study, we conducted a multi-stage study to identify HCC-related mutations in the r...

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Detalles Bibliográficos
Autores principales: Wu, Yan, Gan, Yu, Gao, Fumin, Zhao, Zhimei, Jin, Yan, Zhu, Yu, Sun, Zhihan, Wu, Hao, Chen, Taoyang, Wang, Jinbing, Sun, Yan, Fan, Chunsun, Xiang, Yongbing, Qian, Gengsun, Groopman, John D., Gu, Jianren, Tu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006920/
https://www.ncbi.nlm.nih.gov/pubmed/24788140
http://dx.doi.org/10.1371/journal.pone.0094864