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The Human Adenovirus E4-ORF1 Protein Subverts Discs Large 1 to Mediate Membrane Recruitment and Dysregulation of Phosphatidylinositol 3-Kinase

Adenoviruses infect epithelial cells lining mucous membranes to cause acute diseases in people. They are also utilized as vectors for vaccination and for gene and cancer therapy, as well as tools to discover mechanisms of cancer due to their tumorigenic potential in experimental animals. The adenovi...

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Detalles Bibliográficos
Autores principales: Kong, Kathleen, Kumar, Manish, Taruishi, Midori, Javier, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006922/
https://www.ncbi.nlm.nih.gov/pubmed/24788832
http://dx.doi.org/10.1371/journal.ppat.1004102