High-Efficiency Targeted Editing of Large Viral Genomes by RNA-Guided Nucleases

A facile and efficient method for the precise editing of large viral genomes is required for the selection of attenuated vaccine strains and the construction of gene therapy vectors. The type II prokaryotic CRISPR-Cas (clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Ca...

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Detalles Bibliográficos
Autores principales: Bi, Yanwei, Sun, Le, Gao, Dandan, Ding, Chen, Li, Zhihua, Li, Yadong, Cun, Wei, Li, Qihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006927/
https://www.ncbi.nlm.nih.gov/pubmed/24788700
http://dx.doi.org/10.1371/journal.ppat.1004090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006927/
https://www.ncbi.nlm.nih.gov/pubmed/24788700
http://dx.doi.org/10.1371/journal.ppat.1004090

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