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Life and times: synthesis, trafficking, and evolution of VSG

Evasion of the acquired immune response in African trypanosomes is principally mediated by antigenic variation, the sequential expression of distinct variant surface glycoproteins (VSGs) at extremely high density on the cell surface. Sequence diversity between VSGs facilitates escape of a subpopulat...

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Detalles Bibliográficos
Autores principales: Manna, Paul T., Boehm, Cordula, Leung, Ka Fai, Natesan, Senthil Kumar, Field, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007029/
https://www.ncbi.nlm.nih.gov/pubmed/24731931
http://dx.doi.org/10.1016/j.pt.2014.03.004