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Cloning, Expression and Purification of L. Donovani Specific Antigen for Serodiagnosis of Visceral Leishmaniasis

BACKGROUND: Rapid diagnostic test using rk39 antigen is widely used for visceral leishmaniasis. However it detects anti-rk39 antibodies in 20-32% of endemic healthy individuals. In search for a better biomarker of infection, we identified a protein of molecular weight 70 kDa (BHUP1), specifically re...

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Detalles Bibliográficos
Autores principales: Kumar, Dinesh, Tiwary, Puja, Dube, Anuradha, Chakravarty, Jaya, Rai, Madhukar, Sundar, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007064/
https://www.ncbi.nlm.nih.gov/pubmed/24795833