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Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors

Cardiac progenitor cells (CPCs) must control their number and fate to sustain the rapid heart growth during development, yet the intrinsic factors and environment governing these processes remain unclear. Here, we show that deletion of the ancient cell-fate regulator Numb (Nb) and its homologue Numb...

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Detalles Bibliográficos
Autores principales: Shenje, Lincoln T, Andersen, Peter, Uosaki, Hideki, Fernandez, Laviel, Rainer, Peter P, Cho, Gun-sik, Lee, Dong-ik, Zhong, Weimin, Harvey, Richard P, Kass, David A, Kwon, Chulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007206/
https://www.ncbi.nlm.nih.gov/pubmed/24843018
http://dx.doi.org/10.7554/eLife.02164