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Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy
BACKGROUND: Radiotherapy provides high-cure rates in prostate cancer. Despite its overall slow clinical growth, high proliferation rates documented in a subset of tumours relate to poor radiotherapy outcome. This study examines the role of anaerobic metabolism in prostate cancer growth and resistanc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007238/ https://www.ncbi.nlm.nih.gov/pubmed/24714743 http://dx.doi.org/10.1038/bjc.2014.158 |