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Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy

BACKGROUND: Radiotherapy provides high-cure rates in prostate cancer. Despite its overall slow clinical growth, high proliferation rates documented in a subset of tumours relate to poor radiotherapy outcome. This study examines the role of anaerobic metabolism in prostate cancer growth and resistanc...

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Detalles Bibliográficos
Autores principales:	Koukourakis, M I, Giatromanolaki, A, Panteliadou, M, Pouliliou, S E, Chondrou, P S, Mavropoulou, S, Sivridis, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007238/ https://www.ncbi.nlm.nih.gov/pubmed/24714743 http://dx.doi.org/10.1038/bjc.2014.158

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