Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function

BACKGROUND: Xanthurenic acid is an endogenous molecule produced by tryptophan degradation, produced in the cytoplasm and mitochondria. Its accumulation can be observed in aging-related diseases, e.g. senile cataract and infectious disease. We previously reported that xanthurenic acid provokes apopto...

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Detalles Bibliográficos
Autores principales: Malina, Halina Z, Hess, Otto M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400728/
https://www.ncbi.nlm.nih.gov/pubmed/15068490
http://dx.doi.org/10.1186/1471-2121-5-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC400728/
https://www.ncbi.nlm.nih.gov/pubmed/15068490
http://dx.doi.org/10.1186/1471-2121-5-14

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