Gene Family Level Comparative Analysis of Gene Expression in Mammals Validates the Ortholog Conjecture

The ortholog conjecture (OC), which is central to functional annotation of genomes, posits that orthologous genes are functionally more similar than paralogous genes at the same level of sequence divergence. However, a recent study challenged the OC by reporting a greater functional similarity, in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogozin, Igor B., Managadze, David, Shabalina, Svetlana A., Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007545/
https://www.ncbi.nlm.nih.gov/pubmed/24610837
http://dx.doi.org/10.1093/gbe/evu051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007545/
https://www.ncbi.nlm.nih.gov/pubmed/24610837
http://dx.doi.org/10.1093/gbe/evu051

Ejemplares similares