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Improving reliability and absolute quantification of human brain microarray data by filtering and scaling probes using RNA-Seq
BACKGROUND: High-throughput sequencing is gradually replacing microarrays as the preferred method for studying mRNA expression levels, providing nucleotide resolution and accurately measuring absolute expression levels of almost any transcript, known or novel. However, existing microarray data from...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007560/ https://www.ncbi.nlm.nih.gov/pubmed/24564186 http://dx.doi.org/10.1186/1471-2164-15-154 |