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Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor

Matrine, a clinical drug in China, has been used to treat viral hepatitis, cardiac arrhythmia and skin inflammations. Matrine also exhibits chemotherapeutic potential through its ability to trigger cancer cell death. However, the mechanisms involved are still largely unknown. The objective of this s...

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Detalles Bibliográficos
Autores principales: Zhou, Huan, Xu, Minying, Gao, Ya, Deng, Zhigang, Cao, Hanwei, Zhang, Wenqing, Wang, Qiao, Zhang, Bing, Song, Gang, Zhan, Yanyan, Hu, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007561/
https://www.ncbi.nlm.nih.gov/pubmed/24628719
http://dx.doi.org/10.1186/1476-4598-13-59